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Influenza Antiviral Information
Antiviral medications can be used to treat and prevent influenza virus infections.  There are four antiviral drugs approved for use in the United States.  Use of antiviral medications for the treatment and prevention of influenza is summarized in the Prevention & Control of Influenza - Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2008
   
NEW Interim Recommendations for the Use of Influenza Antivirals for the 2008-2009 Season
   
Antiviral Resistance
   
North Dakota resistance testing since October 1, 2008 -- last updated 3/28/2009
♦To date, 21 isolates have been submitted to CDC for further testing -- results pending
  Resistant isolates identified in the following counties:  Burleigh (1), Morton (1)
. Isolates
tested (n)
Resistant Viruses,
Number (%)
Isolates
tested (n)
Resistant Viruses,
Number (%)
Oseltamivir Zanamivir Adamantanes
Influenza A
(H1N1)
1 1 (100%) 0 (0%) 1 0 (0%)
Influenza A
(H3N2)
1 0 (0%) 0 (0%) 1 1 (100%)
Influenza B 0 0 (0) 0 (0) N/A* N/A*
* adamantanes (amantadine and rimantadine) are not effective against influenza B viruses
† resistance testing performed by Centers for Disease Control and Prevention
   
Nation-wide resistance testing since October 1, 2008 -- last updated 3/28/2009
. Isolates
tested (n)
Resistant Viruses,
Number (%)
Isolates
tested (n)
Resistant Viruses,
Number (%)
Oseltamivir Zanamivir Adamantanes
Influenza A
(H1N1)
654 649 (99.2%) 0 (0) 605 3 (0.5%)
Influenza A
(H3N2)
94 0 (0) 0 (0) 94 94 (100%)
Influenza B 274 0 (0) 0 (0) N/A* N/A*
* adamantanes (amantadine and rimantadine) are not effective against influenza B viruses
† resistance testing performed by Centers for Disease Control and Prevention
   
Links to CDC Educational and Reference Material
red bullet Antiviral Drugs for Seasonal Influenza
red bullet Key Facts About Antiviral Drugs
red bullet Influenza Antiviral Drug Resistance
red bullet Summary of Antiviral Guidance for 2008-2009 Season -- for Healthcare Professionals